УДК 639.11:577.2
REPROGRAMMING OF A CELLS MAMMALIAN GENOME (review)
I.P. Savchenkova
The key questions of nuclear transfer methodology at a cell level are discussed. The recon-struction of embryos by transfer of human cells into enucleated oocytes is one potential source of pluripotent embryonic stem cells. The alternative methods of a cell mammalian genome reprogram-ming: hybridization between stem and differentiated cells and treatment by cell extract are discussed.
Key words: nuclear reprogramming, nuclear transfer, enucleation, embryonic stem cells, toti-and pluripotent, cellular hybridization, cell-free extracts.
ГНУ Всероссийский НИИ экспериментальной |
Поступила в редакцию |