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doi: 10.15389/agrobiology.2021.2.245eng

UDC: 636.2:579.62:579.887

 

Mycoplasma bovis, M. bovigenitalium AND M. dispar AS BOVINE PATHOGENS: BRIEF CHARACTERISTICS OF THE PATHOGENS(review)

M. Abed Alhussen1, V.V. Kirpichenko2, S.P. Yatsentyuk3,
A.A. Nesterov2, O.P. Byadovskaya2, T.V. Zhbanova2,
A.V. Sprygin2 ✉

1People’s Friendship University of Russia (RUDN University), 6, ul. Miklukho-Maklaya, Moscow, 117198 Russia, e-mail alhussenmohammed85@hotmail.com;
2Federal Center for Animal Health Control, FGBU VNIIZZh, mkr. Yurievets, Vladimir, 600901 Russia, e-mail kirpichenko@arriah.ru, nesterov@arriah.rubjadovskaya@arriah.ru, zhbanova@arriah.ru, sprygin@arriah.ru (✉ corresponding author);
3Russian State Center for Animal Feed and Drug Standardization and Quality, 5, Zvenigorodskoe sh., Moscow, 123022 Russia, e-mail pcr-lab@vgnki.ru

ORCID:
Abed Alhussen M. orcid.org/0000-0002-1210-0303
Byadovskaya O.P. orcid.org/0000-0002-8326-7151
Kirpichenko V.V. orcid.org/0000-0002-2494-3826
Zhbanova T.V. orcid.org/0000-0002-9857-5915
Yatsentyuk S.P. orcid.org/0000-0002-4819-2131
Sprygin A.V. orcid.org/0000-0001-5982-3675
Nesterov A.A. orcid.org/0000-0002-4288-1964

Received December 9, 2020

The cattle mycoplasmas are widespread throughout the world (A.M. Parker et al., 2018; M. Abed Alhussen et al., 2020). This review presents data on the epidemiology and diagnosis of mycoplasmosis in cattle caused by M. bovis, M. bovigenitalium, and M. dispar. Mycoplasmas can cause economically important diseases in cattle, including mastitis, arthritis, keratoconjunctivitis, otitis media, pneumonia, and reproductive disorders (R.A.J. Nicholas et al., 2008; F.P. Maunsell et al., 2011). Mycoplasmas are characterized by a size of up to 150 μm, small genome (0.58-1.38 million base pairs) a low G-C composition (23-40 %) and the absence of a cell wall which determines their polymorphism and resistance to antibiotics, influencing the synthesis of the bacterial cell wall (R.A.J. Nicholas et al., 2008; P. Vos et al., 2011). Mycoplasma surface antigens are highly variable both in vitro and in vivo, which leads to significant variability of isolates (M.A. Rasheed et al., 2017). They also play an important role in overcoming the host’s immune system. In addition, some of these antigens are involved in the adhesion of mycoplasmas to host cells (Y. Guo et al., 2017). After adhesion, many mycoplasmas produce a variety of products that damage host cells and enhance pathogenesis (L.A. Khan et al., 2005). They can also form biofilms that increase resistance to drying out and heat stress (L. McAuliffe et al., 2006; F. Gomes et al., 2016). Moreover, the invasion and intracellular survival of mycoplasmas in cattle cells contributes to the preservation and spread in the host organism (J. Van der Merwe et al., 2010). The incubation period for mycoplasma infection in cattle depends on many factors, i.e., the infectious dose, the presence of associated infections, the conditions of keeping the animals in the herd and the stress state of the animals (M.J. Calcutt et al., 2018). Sick animals are a source of infection, because they can shed the pathogen with nasal discharge and sperm for several months and sometimes for several years (K.A. Clothier et al., 2010; V. Punyapornwithaya et al., 2010). It should be noted that at low temperatures, mycoplasmas remain viable for a long time: in deeply frozen cattle semen, the pathogen can remain infectious for many years (A. Kumar et al., 2011). The high contagiousness of some species of Mycoplasma spp., their low sensitivity to treatment and the associated consequences of culling for the affected population make timely and accurate diagnosis important for disease control and prevention (A.M. Parker et al., 2018). The cultural methods can be applied for isolation and identification of the pathogen. However, these methods have limitations. Cultivation of mycoplasmas requires a complex medium, special equipment and technical skills (R.A.J. Nicholas et al., 2008; M.J. Calcutt et al., 2018; A.M. Andersson et al., 2019). Mycoplasmas require 7-10-day cultivation at a temperature of 37 °Сand 5-10 % CO2. The colony has the “Fried-egg” appearance characteristic of most mycoplasmas (P.J. Quinn et al., 2011). By contrast, PCR provides a rapid and accurate diagnosis of the disease by detecting mycoplasmal DNA (A.M. Andersson et al., 2019). Furthermore, many other methods of diagnostics of bovine mycoplasma are used, such as MALDI-TOF MS (Matrix assisted laser desorption ionization time-of-light mass spectrometry), latex agglutination, immunochromatographic assays etc., however, each method has its advantages and disadvantages, which should be considered before application (M.J. Calcutt et al., 2018; B. Pardon et al., 2020).

Keywords: Mycoplasma bovis, Mycoplasma bovigenitalium, Mycoplasma dispar, cattle, pathogens, epidemiology.

 

REFERENCES

  1. Bergey’s manual® of systematic bacteriology. Volume 3: The Firmicutes. P. Vos, G. Garrity, D. Jones, N.R. Krieg, W. Ludwig, F.A. Rainey, K.H. Schleifer, W.B. Whitman (eds.). Springer Science & Business Media, 2011 CrossRef
  2. Nocard M., Roux M., Borrel M., Salimbeniet M., Dujardin-Beaumetz M.The microbe of pleuropneumonia. Reviews of Infectious Diseases, 1990, 12(2): 354-358 CrossRef
  3. Dupuy V., Manso-Silván L., Barbe V., Thebault P., Dordet-Frisoni E., Citti C., Poumarat F., Blanchard A., Breton M., Sirand-Pugnet P., Thiaucourt F. Evolutionary history of contagious bovine pleuropneumonia using next generation sequencing of Mycoplasma mycoides subsp. mycoides “small colony”. PLoS ONE, 2012, 7(10): e46821 CrossRef
  4. Manso-Silván L., Dupuy V., Lysnyansky I., Ozdemir U., Thiaucourt F. Phylogeny and molecular typing of Mycoplasma agalactiae and Mycoplasma bovis by multilocus sequencing. Veterinary microbiology, 2012, 161(1-2): 104-112 CrossRef
  5. Mycoplasma protocols. R.J. Miles, R.A.J. Nicholas (eds.). Humana Press, 1998 CrossRef
  6. Mycoplasma diseases of ruminants. R. Nicholas, R. Ayling, L. McAuliffe (eds.).Wallingford, CABI, 2008 CrossRef
  7. Quinn P.J., Markey B.K., Leonard F.C., Hartigan P., Fanning S., Fitzpatrick E.S. Veterinary microbiology and microbial disease, 2nd Edition. Wiley-Blackwell, 2011.
  8. Maunsell F.P., Woolums A.R., Francoz D., Rosenbusch R.F., Step D.L., Wilson D.J., Janzen E.D. Mycoplasma bovis infections in cattle. Journal of Veterinary Internal Medicine, 2011, 25(4): 772-783 CrossRef
  9. Pitcher D.G., Nicholas R.A.J. Mycoplasma host specificity: fact or fiction? The Veterinary Journal, 2005, 170(3): 300-306 CrossRef
  10. Radaelli E., Luini M., Loria G.R., Nicholas R.A.J., Scanziani E. Bacteriological, serological, pathological and immunohistochemical studies of Mycoplasma bovis respiratory infection in veal calves and adult cattle at slaughter. Research in Veterinary Science, 2008, 85(2): 282-290 CrossRef
  11. Caswell J.L., Archambault M. Mycoplasma bovis pneumonia in cattle. Animal Health Research Reviews, 2007, 8(2): 161-186 CrossRef
  12. Rodríguez F., Bryson D.G., Ball H.J., Forster F. Pathological and immunohistochemical studies of natural and experimental Mycoplasma bovis pneumonia in calves. Journal of Comparative Pathology, 1996, 115(2): 151-162 CrossRef
  13. Maunsell F.P., Donovan G.A. Mycoplasma bovis infections in young calves. Veterinary Clinics of North America: Food Animal Practice, 2009, 25(1): 139-177 CrossRef
  14. Nicholas R.A.J., Fox L.K., Lysnyansky I. Mycoplasma mastitis in cattle: To cull or not to cull. The Veterinary Journal, 2016, 216: 142-147 CrossRef
  15. Houlihan M.G., Veenstra B., Christian M.K., Nicholas R., Ayling R. Mastitis and arthritis in two dairy herds caused by Mycoplasma bovis. Veterinary Record, 2007, 160(4): 126-127 CrossRef
  16. Wilson D.J., Skirpstunas R.T., Trujillo J.D., Cavender K.B., Bagley C.V., Harding R.L. Unusual history and initial clinical signs of Mycoplasma bovis mastitis and arthritis in first-lactation cows in a closed commercial dairy herd. Journal of the American Veterinary Medical Association, 2007, 230(10): 1519-1523 CrossRef
  17. Ross R.F.Mycoplasma — animal pathogens. In: Rapid diagnosis of mycoplasmas. Federation of European microbilogical societies symposium series, vol. 62. Springer, Boston, MA, 1993: 69-109 CrossRef
  18. Nicholas R.A.J., Ayling R.D. Mycoplasma bovis: disease, diagnosis, and control. Research in Veterinary Science, 2003, 74(2): 105-112 CrossRef
  19. Lysnyansky I., Brenner J., Bernstein M., Elad D., Blum S., Friedgut O., Rotenberg D., Alpert N., Benjamin A. Identification of Mycoplasma bovigenitalium and Mycoplasma canadense from outbreaks of granulopapular vulvovaginitis in dairy cattle in Israel. Veterinary Record, 2009, 165(11): 319-322 CrossRef
  20. Parker A.M., Sheehy P.A., Hazelton M.S., Bosward K.L., House J.K. A review of mycoplasma diagnostics in cattle. Journal of Veterinary Internal Medicine, 2018, 32(3): 1241-1252 CrossRef
  21. Ter Laak E.A., Noordergraaf J.H., Boomsluiter E. The nasal mycoplasmal flora of healthy calves and cows. Journal of Veterinary Medicine, Series B, 1992, 39(1-10): 610-616 CrossRef
  22. Ter Laak E.A., Noordergraaf J.H., Dieltjes R.P.J.W. Prevalence of mycoplasmas in the respiratory tracts of pneumonic calves. Journal of Veterinary Medicine, Series B, 1992, 39(1-10): 553-562 CrossRef
  23. Tegtmeier C., Uttenthal A., Friis N.F., Jensen N.E., Jensen H.E. Pathological and microbiological studies on pneumonic lungs from Danish calves. Journal of Veterinary Medicine, Series B, 1999, 46(10): 693-700 CrossRef
  24. Dabo S.M., Taylor J.D., Confer A.W. Pasteurella multocida and bovine respiratory disease. Animal Health Research Reviews, 2008, 8(2): 129-150 CrossRef
  25. Almeida R.A., Rosenbusch R.F. Capsulelike surface material of Mycoplasma dispar induced by in vitro growth in culture with bovine cells is antigenically related to similar structures expressed in vivo. Infection and Immunity, 1991, 59(9): 3119-3125 CrossRef
  26. Ayling R.D., Bashiruddin S.E., Nicholas R.A.J. Mycoplasma species and related organisms isolated from ruminants in Britain between 1990 and 2000. Veterinary Record, 2004, 155(14): 413-416 CrossRef
  27. Taylor G. Immunity to mycoplasma infections of the respiratory tract: a review. Journal of the Royal Society of Medicine, 1979, 72(7): 520-526 CrossRef
  28. Gourlay R.N., Howard C.J., Thomas L.H., Wyld S.G. Pathogenicity of some Mycoplasma and Acholeplasma species in the lungs of gnotobiotic calves. Research in Veterinary Science, 1979, 27(2): 233-237 CrossRef
  29. Bürki S., Frey J., Pilo P. Virulence, persistence and dissemination of Mycoplasma bovis. Veterinary Microbiology, 2015, 179(1-2): 15-22 CrossRef
  30. O’Brien D., Scudamore J., Charlier J., Delavergne M. DISCONTOOLS: a database to identify research gaps on vaccines, pharmaceuticals and diagnostics for the control of infectious diseases of animals. BMC Veterinary Research, 2016, 13: 1 CrossRef
  31. Abed Alkhussen M., Nesterov A.A., Kirpichenko V.V., Yatsentyuk S.P., Sprygin A.V., B'yadovskaya O.P., Kononov A.V. Veterinariya segodnya, 2020, 2: 102-108 CrossRef (in Russ.).
  32. Langford E.V. Isolation of Mycoplasma bovigenitalium from an aborted equine foetus. Veterinary Record, 1974, 94(23): 528 CrossRef
  33. Macêdo A.A.M., Oliveira J.M.B., Silva B.P., Borges J.M., Soares L.B.F., Silva G.M., Santos S.B., Mota R.A., Pinheiro-Júnior J.W. Occurrence of Mycoplasma bovigenitalium and Ureaplasma diversum in dairy cattle from to Pernambuco state, Brazil. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2018, 70(6): 1798-1806 CrossRef
  34. Ose E.E., Muenster O.A. Isolation of Mycoplasma dispar from cattle in the United States. Veterinary Record, 1975, 97: 11 CrossRef
  35. Tortorelli G., Carrillo Gaeta N., Mendonça Ribeiro B.L., Miranda Marques L., Timenetsky J., Gregory L. Evaluation of Mollicutes microorganisms in respiratory disease of cattle and their relationship to clinical signs. Journal of Veterinary Internal Medicine, 2017, 31(4): 1215-1220 CrossRef
  36. Gourlay R.N., Leach R.H. A new mycoplasma species isolated from pneumonic lungs of calves (Mycoplasma dispar sp. nov.). Journal of Medical Microbiology, 1970, 3(1): 111-123 CrossRef
  37. França Dias de Oliveira B.A., Carrillo Gaeta N., Mendonça Ribeiro B.L., Reyes Alemán M.A., Miranda Marques L., Timenetsky J., Melville P.A., Avansi Marques J., Marvulle V., Gregory L. Determination of bacterial aetiologic factor on tracheobronchial lavage in relation to clinical signs of bovine respiratory disease. Journal of Medical Microbiology, 2016, 65(10): 1137-1142 CrossRef
  38. Bottinelli M., Passamonti F., Rampacci E., Stefanetti V., Pochiero L., Coletti M., Rueca F., Hyatt D.R., Schnee C. DNA microarray assay and real-time PCR as useful tools for studying the respiratory tract Mycoplasma populations in young dairy calves. Journal of Medical Microbiology, 2017, 66(9): 1342-1349 CrossRef
  39. Veterinary microbiology, 3rd Edition. D.S. McVey, M. Kennedy, M.M. Chengappa (eds.). Wiley-Blackwell, 2013.
  40. Khan L.A., Miles R.J., Nicholas R.A.J. Hydrogen peroxide production by Mycoplasma bovis and Mycoplasma agalactiae and effect of in vitro passage on a Mycoplasma bovis strain producing high levels of H2O2. Veterinary Research Communications, 2005, 29(3): 181-188 CrossRef
  41. Zhao G., Zhang H., Chen X., Zhu X., Guo Y., He C., Anwar Khan F., Chen Y., Hu C., Chen H., Guo A. Mycoplasma bovis NADH oxidase functions as both a NADH oxidizing and O2 reducing enzyme and an adhesin. Scientific Reports, 2017, 7(1): 44 CrossRef
  42. Cole B.C., Ward J.R., Martin C.H. Hemolysin and peroxide activity of Mycoplasma species. Journal of Bacteriology, 1968, 95(6): 2022-2030 CrossRef
  43. Nicholas R.A., Lin Y.C., Sachse K., Hotzel H., Parham K., McAuliffe L., Miles R. J., Kelly D.P., Wood A.P. Proposal that the strains of the Mycoplasma ovine/caprine serogroup 11 be reclassified as Mycoplasma bovigenitalium. International Journal of Systematic and Evolutionary Microbiology, 2008, 58(1): 308-312 CrossRef
  44. Nicholas R.A., Khan L.A., Houshaymi B., Miles R.J., Ayling R.D., Hotzel H., Sachse K. Close genetic and phenotypic relatedness between Mycoplasma ovine/caprine serogroup 11 and Mycoplasma bovigenitalium. Systematic and Applied Microbiology, 2002, 25(3): 396-402 CrossRef
  45. Uphoff C.C., Drexler H.G. Detection of mycoplasma contamination in cell cultures. Current Protocols in Molecular Biology, 2014, 106(1): 24-28 CrossRef
  46. Klein U., de Jong A., Youala M., El Garch F., Stevenin C., Moyaert H., Rose M., Catania S., Gyuranecz M., Pridmore A., Ayling R.D. New antimicrobial susceptibility data from monitoring of Mycoplasma bovis isolated in Europe. Veterinary Microbiology, 2019, 238: 108432 CrossRef
  47. Chernova O.A., Medvedeva E.S., Muzykantov A.A., Baranova N.B., Chernov V.M. Acta Naturae, 2016, 8(2): 27-38 CrossRef (in Russ.).
  48. Maes D., Boyen F., Haesebrouck F., Gautier-Bouchardon A.V. Antimicrobial treatment of Mycoplasma hyopneumoniae infections. The Veterinary Journal, 2020, 259-260: 105474 CrossRef
  49. Gautier‐Bouchardon A.V. Antimicrobial resistance in Mycoplasma spp. In: Antimicrobial resistance in bacteria from livestock and companion animals. S. Schwarz, L.M. Cavaco, J. Shen (eds). American Society of Microbiology Press, 2018: 425-446 CrossRef
  50. Lysnyansky I., Ayling R.D. Mycoplasma bovis: mechanisms of resistance and trends in antimicrobial susceptibility. Frontiers in Microbiology, 2016, 7: 595 CrossRef
  51. Reinhardt A.K., Kempf I., Kobisch M., Gautier-Bouchardon A.V. Fluoroquinolone resistance in Mycoplasma gallisepticum: DNA gyrase as primary target of enrofloxacin and impact of mutations in topoisomerases on resistance level. Journal of Antimicrobial Chemotherapy, 2002, 50(4): 589-592 CrossRef
  52. Amram E., Mikula I., Schnee C., Ayling R.D., Nicholas R.A., Rosales R.S., Harrus S., Lysnyansky I. 16S rRNA gene mutations associated with decreased susceptibility to tetracycline in Mycoplasma bovis. Antimicrobial Agents and Chemotherapy, 2015, 59(2): 796-802 CrossRef
  53. Kumar A., Verma A.K., Rahal A. Mycoplasma bovis, a multi disease producing pathogen: an overview. Asian Journal of Animal and Veterinary Advances, 2011, 6(6): 537-546 CrossRef
  54. Pfützner H. Tenazität von Mycoplasma bovis. Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1984, 258(1): 38-41 CrossRef
  55. Wilson D.J., Justice-Allen A., Goodell G., Baldwin T.J., Skirpstunas R.T., Cavender K.B. Risk of Mycoplasma bovis transmission from contaminated sand bedding to naive dairy calves. Journal of Dairy Science, 2011, 94(3): 1318-1324 CrossRef
  56. Justice-Allen A., Trujillo J., Corbett R., Harding R., Goodell G., Wilson D. Survival and replication of Mycoplasma species in recycled bedding sand and association with mastitis on dairy farms in Utah. Journal of Dairy Science, 2010, 93(1): 192-202 CrossRef
  57. Aebi M., van den Borne B., Raemy A., Steiner A., Pilo P., Bodmer M. Mycoplasma bovis infections in Swiss dairy cattle: a clinical investigation. Acta Veterinaria Scandinavica, 2015, 57(1): 10 CrossRef
  58. Amram E., Freed M., Khateb N., Mikula I., Blum S., Spergser J., Sharir B., Ozeri R., Harrus S., Lysnyansky I. Multiple locus variable number tandem repeat analysis of Mycoplasma bovis isolated from local and imported cattle. The Veterinary Journal, 2013, 197(2): 286-290 CrossRef
  59. Arede M., Nielsen P.K., Ahmed S.S.U., Halasa T., Nielsen L.R., Toft N. A space-time analysis of Mycoplasma bovis: bulk tank milk antibody screening results from all Danish dairy herds in 2013-2014. Acta Veterinaria Scandinavica, 2016, 58(1): 16 CrossRef
  60. Visser I.J., ter Laak E.A., Jansen H.B. Failure of antibiotics gentamycin, tylosin, lincomycin and spectinomycin to eliminate Mycoplasma bovis in artificially infected frozen bovine semen. Theriogenology, 1999, 51(4): 689-697 CrossRef
  61. Bielanski A., Eaglesome M.D., Ruhnke H.L., Hare W.C.D. Isolation of Mycoplasma bovis from intact and microinjected preimplantation bovine embryos washed or treated with trypsin or antibiotics. Journal of in Vitro Fertilization and Embryo Transfer, 1989, 6(4): 236-241 CrossRef
  62. Kozlova A.D., Gorbacheva N.S., Khaerova R.F., Krasnikova M.S., Lazareva E.A., Yatsentyuk S.P. Differentiation of Mycoplasma bovis, Mycoplasma bovigenitalium, Mycoplasma californicum and identification of ureaplasma diversum by real-time PCR. Agricucltural Biology [Sel'skokhozyaistvennaya biologiya], 2019, 54(2): 378-385 CrossRef
  63. Biddle M.K., Fox L.K., Hancock D.D. Patterns of mycoplasma shedding in the milk of dairy cows with intramammary mycoplasma infection. Journal of the American Veterinary Medical Association, 2003, 223(8): 1163-1166 CrossRef
  64. Punyapornwithaya V., Fox L.K., Hancock D.D., Gay J.M., Alldredge J.R. Association between an outbreak strain causing mycoplasma bovis mastitis and its asymptomatic carriage in the herd: a case study from Idaho, USA. Preventive Veterinary Medicine, 2010, 93(1): 66-70 CrossRef
  65. Woldehiwet Z., Mamache B., Rowan T.G. Effects of age, environmental temperature and relative humidity on the colonization of the nose and trachea of calves by Mycoplasma spp. British Veterinary Journal, 1990, 146(5): 419-424 CrossRef
  66. Punyapornwithaya V., Fox L.K., Hancock D.D., Gay J.M., Wenz J.R., Alldredge J.R. Incidence and transmission of Mycoplasma bovis mastitis in Holstein dairy cows in a hospital pen: A case study. Preventive Veterinary Medicine, 2011, 98(1): 74-78 CrossRef
  67. Pfützner H., Sachse K. Mycoplasma bovis as an agent of mastitis, pneumonia, arthritis and genital disorders in cattle. Revue Scientifique et Technique-Office International des Epizooties, 1996, 15(4): 1477-1494 CrossRef
  68. Calcutt M.J., Lysnyansky I., Sachse K., Fox L.K., Nicholas R.A.J., Ayling R.D. Gap analysis of Mycoplasma bovis disease, diagnosis and control: An aid to identify future development requirements. Transboundary and Emerging Diseases, 2018, 65(S1): 91-109 CrossRef
  69. Razin S., Jacobs E. Mycoplasma adhesion. Journal of General Microbiology, 1992, 138(3): 407-422 CrossRef
  70. Sachse K., Grajetzki C., Rosengarten R., Hänel I., Heller M., Pfützner H. Mechanisms and factors involved in Mycoplasma bovis adhesion to host cells. Zentralblatt für Bakteriol, 1996, 284(1): 80-92 CrossRef
  71. Song Z., Li Y., Liu Y., Xin J., Zou X., Sun W. a-Enolase, an adhesion-related factor of Mycoplasma bovis. PLoS ONE, 2012, 7(6): e38836 CrossRef
  72. Sachse K., Helbig J.H., Lysnyansky I., Grajetzki C., Müller W., Jacobs E., Yogev D. Epitope mapping of immunogenic and adhesive structures in repetitive domains of Mycoplasma bovis variable surface lipoproteins. Infection and Immunity, 2000, 68(2): 680-687 CrossRef
  73. Zou X., Li Y., Wang Y., Zhou Y., Liu Y., Xin J. Molecular cloning and characterization of a surface-localized adhesion protein in Mycoplasma bovis Hubei-1 strain. PLoS ONE, 2013, 8(7): e69644 CrossRef
  74. McAuliffe L., Ellis R.J., Miles K., Ayling R.D., Nicholas R.A.J. Biofilm formation by mycoplasma species and its role in environmental persistence and survival. Microbiology, 2006, 152(4): 913-922 CrossRef
  75. Shaw B.M., Simmons W.L., Dybvig K. The Vsa shield of Mycoplasma pulmonis is antiphagocytic. Infection and Immunity, 2012, 80(2): 704-709 CrossRef
  76. Citti C., Kim M.F., Wise K.S. Elongated versions of Vlp surface lipoproteins protect Mycoplasma hyorhinis escape variants from growth-inhibiting host antibodies. Infection and Immunity, 1997, 65(5): 1773-1785 CrossRef
  77. Guo Y., Zhu H., Wang J., Huang J., Khan F. A., Zhang J., Guo A., Chen X. TrmFO, a fibronectin-binding adhesin of Mycoplasma bovis. International journal of molecular sciences., 2017, 18(8): 1732 CrossRef
  78. van der Merwe J., Prysliak T., Perez-Casal J. Invasion of bovine peripheral blood mononuclear cells and erythrocytes by Mycoplasma bovis. Infection and Immunity, 2010, 78(11): 4570-4578 CrossRef
  79. Maeda T., Shibahara T., Kimura K., Wada Y., Sato K., Imada Y., Ishikawa Y., Kadota K. Mycoplasma bovis-associated suppurative otitis media and pneumonia in bull calves. Journal of comparative pathology, 2003, 129(2-3): 100-110 CrossRef
  80. Suleman M., Prysliak T., Clarke K., Burrage P., Windeyer C., Perez-Casal J. Mycoplasma bovis isolates recovered from cattle and bison (Bison bison) show differential in vitro effects on PBMC proliferation, alveolar macrophage apoptosis and invasion of epithelial and immune cells. Veterinary Microbiology, 2016, 186: 28-36 CrossRef
  81. Simmons W.L., Daubenspeck J.M., Osborne J.D., Balish M.F., Waites K.B., Dybvig K. Type 1 and type 2 strains of Mycoplasma pneumoniae form different biofilms. Microbiology, 2013, 159(Pt 4): 737-747 CrossRef
  82. Wang Y., Yi L., Zhang F., Qiu X., Tan L., Yu S., Cheng X., Ding C. Identification of genes involved in Mycoplasma gallisepticum biofilm formation using mini-Tn4001-SGM transposon mutagenesis. Veterinary Microbiology, 2017, 198: 17-22 CrossRef
  83. Gomes F., Saavedra M.J., Henriques M. Bovine mastitis disease/pathogenicity: evidence of the potential role of microbial biofilms. Pathogens and Disease, 2016, 74(3): ftw006 CrossRef
  84. Melchior M.B., Vaarkamp H., Fink-Gremmels J. Biofilms: a role in recurrent mastitis infections? The Veterinary Journal, 2006, 171(3): 398-407 CrossRef
  85. McAuliffe L., Ayling R.D., Ellis R.J., Nicholas R.A.J. Biofilm-grown Mycoplasma mycoides subsp. mycoides SC exhibit both phenotypic and genotypic variation compared with planktonic cells. Veterinary Microbiology, 2008, 129(3-4): 315-324 CrossRef
  86. Whitman R., Harwood V.J., Edge T.A., Nevers M., Byappanahalli M., Vijayavel K., Brandão J., Sadowsky M. J., Alm E.W., Crowe A., Ferguson D., Ge Z., Halliday E., Kinzelman J., Kleinheinz G., Przybyla-Kelly K., Staley C., Staley Z., Solo-Gabriele H.M. Microbes in beach sands: integrating environment, ecology and public health. Reviews in Environmental Science and Bio/Technology, 2014, 13(3): 329-368 CrossRef
  87. Rasheed M.A., Qi J., Zhu X., Chenfei H., Menghwar H., Khan F.A., Zhao G., Zubair M., Hu C., Chen Y., Chen H., Guo A. Comparative genomics of Mycoplasma bovis strains reveals that decreased virulence with increasing passages might correlate with potential virulence-related factors. Frontiers in Cellular and Infection Microbiology, 2017, 7: 177 CrossRef
  88. Andersson A., Aspán A., Wisselink H.J., Smid B., Ridley A.M., Pelkonen S., Autio T., Lauritsen K.T., Kensø J., Gaurivaud P., Tardy F. A European inter-laboratory trial to evaluate the performance of three serological methods for diagnosis of Mycoplasma bovis infection in cattle using latent class analysis. BMC Veterinary Research, 2019, 15(1): 369 CrossRef
  89. Clothier K.A., Jordan D.M., Thompson C.J., Kinyon J.M., Frana T.S., Strait E.L. Mycoplasma Bovis real-time polymerase chain reaction assay validation and diagnostic performance. Journal of Veterinary Diagnostic Investigation, 2010, 22(6): 956-960 CrossRef
  90. Bokma J., Van Driessche L., Deprez P., Haesebrouck F., Vahl M., Weesendorp E., Deurenberg R.H., Pardon B., Boyen F. Rapid identification of Mycoplasma bovis strains from bovine bronchoalveolar lavage fluid with matrix-assisted laser desorption ionization—time of flight mass spectrometry after enrichment procedure. Journal of Clinical Microbiology, 2020, 58(6): e00004-20 CrossRef
  91. Pardon B., Buczinski S. Bovine respiratory disease diagnosis: what progress has been made in infectious diagnosis? Veterinary Clinics: Food Animal Practice, 2020, 36(2): 425-444 CrossRef
  92. Wisselink H.J., Smid B., Plater J., Ridley A., Andersson A.M., Aspán A., Pohjanvirta T., Vähänikkilä N., Larsen H., Høgberg J., Colin A., Tardy F. A European interlaboratory trial to evaluate the performance of different PCR methods for Mycoplasma bovis diagnosis. BMC Veterinary Research, 2019, 15(1): 86 CrossRef
  93. Pardon B., Callens J., Maris J., Allais L., Van Praet W., Deprez P., Ribbens S. Pathogen-specific risk factors in acute outbreaks of respiratory disease in calves. Journal of Dairy Science, 2020, 103(3): 2556-2566 CrossRef
  94. O’Neill R., Mooney J., Connaghan E., Furphy C., Graham D.A. Patterns of detection of respiratory viruses in nasal swabs from calves in Ireland: a retrospective study. Veterinary Record, 2014, 175(14): 351 CrossRef
  95. Angen O., Thomsen J., Larsen L.E., Larsen J., Kokotovic B., Heegaard P.M., Enemark J.M. Respiratory disease in calves: microbiological investigations on trans-tracheally aspirated bronchoalveolar fluid and acute phase protein response. Veterinary Microbiology, 2009, 137(1-2): 165-171 CrossRef
  96. Sachse K., Salam H.S.H., Diller R., Schubert E., Hoffmann B., Hotzel H. Use of a novel real-time PCR technique to monitor and quantitate Mycoplasma bovis infection in cattle herds with mastitis and respiratory disease. The Veterinary Journal, 2010, 186(3): 299-303 CrossRef
  97. Rossetti B.C., Frey J., Pilo P. Direct detection of Mycoplasma bovis in milk and tissue samples by real-time PCR. Molecular and Cellular Probes, 2010, 24(5): 321-323 CrossRef
  98. Cornelissen J.B., de Bree F.M., van der Wal F.J., Kooi E.A., Koene M.G., Bossers A., Smid B., Antonis A.F., Wisselink H.J. Mycoplasma detection by triplex real-time PCR in bronchoalveolar lavage fluid from bovine respiratory disease complex cases. BMC Veterinary Research, 2017, 13(1): 97 CrossRef
  99. Parker A.M., House J.K., Hazelton M.S., Bosward K.L., Sheehy P.A. Comparison of culture and a multiplex probe PCR for identifying Mycoplasma species in bovine milk, semen and swab samples. G.F. Browning (ed.). PLoS ONE, 2017, 12(3): e0173422 CrossRef
  100. McAuliffe L., Ellis R.J., Lawes J.R., Ayling R.D., Nicholas R.A. 16S rDNA PCR and denaturing gradient gel electrophoresis; a single generic test for detecting and differentiating Mycoplasma species. Journal of Medical Microbiology, 2005, 54(8): 731-739 CrossRef
  101. Schnee C., Schulsse S., Hotzel H., Ayling R.D., Nicholas R.A., Schubert E., Heller M., Ehricht R., Sachse K.A. Novel rapid dna microarray assay enables identification of 37 mycoplasma species and highlights multiple mycoplasma infections. PLoS ONE, 2012, 7(3): e33237 CrossRef
  102. Spergser J., Hess C., Loncaric I., Ramírez A.S. Matrix-assisted laser desorption ionization-time of flight mass spectrometry is a superior diagnostic tool for the identification and differentiation of mycoplasmas isolated from animals. Journal of Clinical Microbiology, 2019, 57(9): e00316-19. CrossRef
  103. Van Driessche L., Bokma J., Deprez P., Haesebrouck F., Boyen F., Pardon B. Rapid identification of respiratory bacterial pathogens from bronchoalveolar lavage fluid in cattle by MALDI-TOF MS. Scientific Reports, 2019, 9(1): 1-8 CrossRef
  104. Edwards D.J., Holt K.E. Beginner’s guide to comparative bacterial genome analysis using next-generation sequence data. Microbial Informatics and Experimentation, 2013, 3(1): 2 CrossRef
  105. Chen S., Hao H., Zhao P., Gao P., He Y., Ji W., Wang Z., Lu Z., Liu Y., Chu Y. Complete genome sequence of Mycoplasma bovis strain 08M. Genome Announcements, 2017, 5(19): e00324-17 CrossRef
  106. Qi J., Guo A., Cui P., Chen Y., Mustafa R., Ba X., Hu C., Bai Z., Chen X., Shi L., Chen H. Comparative geno-plasticity analysis of Mycoplasma bovis HB0801 (Chinese isolate). PLoS ONE, 2012, 7(5): e38239 CrossRef
  107. Sun P., Luo H., Zhang X., Xu J., Guo Y., He S. Whole-genome sequence of Mycoplasma bovis strain Ningxia-1. Genome Announcements, 2018, 6(4): e01367-17 CrossRef
  108. Calcutt M.J., Foecking M.F., Fox L.K. Complete genome sequence of the bovine mastitis pathogen Mycoplasma californicum strain ST-6T (ATCC 33461T). Genome Announcements, 2014, 2(4): e00648-14 CrossRef
  109. Hata E., Murakami K. Complete genome sequence of Mycoplasma californicum strain HAZ160_1 from bovine mastitic milk in Japan. Genome Announcements, 2014, 2(4): e00684-14 CrossRef
  110. Hata E. Complete genome sequence of Mycoplasma arginini strain HAZ 145_1 from bovine mastitic milk in Japan. Genome Announcements, 2015, 3(2): e00265-15 CrossRef
  111. Hata E., Nagai K., Murakami K. Complete genome sequence of Mycoplasma bovigenitalium strain HAZ 596 from a bovine vagina in Japan. Genome Announcements, 2017, 5(6): e01554-16 CrossRef
  112. Hata E. Complete genome sequence of Mycoplasma canadense strain HAZ 360_1 from bovine mastitic milk in Japan. Genome Announcements, 2014, 2(5): e00984-14 CrossRef
  113. Calcutt M.J., Foecking M.F. Complete genome sequence of Mycoplasma bovoculi strain M165/69T (ATCC 29104). Genome Announcements, 2014, 2(1): e00115-14 CrossRef
  114. Wise K.S., Calcutt M.J., Foecking M.F., Madupu R., DeBoy R.T., Röske K., Hvinden M.L., Martin T.R., Durkin A.S., Glass J.I., Methé B.A. Complete genome sequences of Mycoplasma leachii strain PG50T and the pathogenic Mycoplasma mycoides subsp. mycoides small colony biotype strain Gladysdale. Journal of Bacteriology, 2012, 194(16): 4448-4449 CrossRef
  115. Ashraf A., Imran M., Yaqub T., Tayyab M., Shehzad W., Mingala C.N., Chang Y.F. Development and validation of a loop-mediated isothermal amplification assay for the detection of Mycoplasma bovis in mastitic milk. Folia Microbiologica, 2018, 63(3): 373-380 CrossRef
  116. Higa Y., Uemura R., Yamazaki W., Goto S., Goto Y., Sueyoshi M. An improved loop-mediated isothermal amplification assay for the detection of Mycoplasma bovis. Journal of Veterinary Medical Science, 2016, 78(8): 1343-1346 CrossRef

 

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